The symposium will highlight the results of a new study, Decipher cell-type specific longitudinal defects in the pathogenesis of diabetes, assess how type 2 diabetes alters the composition and gene regulatory programs of each cell type in human pancreatic islets using genomic profiling.

In the study, researchers performed genomic profiling of approximately 250,000 cells from 17 non-diabetic, 14 pre-diabetic, and 17 type 2 diabetic individuals, representing the largest single-cell genomic analysis to date, both in the number of cells studied and in the number of non-diabetics, pre-diabetics and type 2 diabetics. The results showed that the islets of type 2 diabetics contained significantly fewer insulin-producing beta cells and identified new misregulated genes.

“These findings help us better understand which genes play a role in islet dysfunction, a major contributor to type 2 diabetes. insulin for people with type 2 diabetes,” said Michael L. StitzelPhD, associate professor at the Jackson Laboratory for Genomic Medicine.

New glucose management

Conclusions were also presented from Freeing Diabetes Through Innovative Engineering evaluate micro-electromechanical systems, microfluidics and bio-sensing to achieve the goal of a painless, minimally invasive, inexpensive, calibration-free and insulin pump compatible CGM. The author will present a proposed solution for the unmet need for a painless and inexpensive disposable patch that can be adopted by people with type I and type 2 and prediabetes.

“One of the primary goals of diabetes management is to restore even glycemic control, thereby avoiding the dangerous side effects of hypoglycemia and hyperglycemia,” says Sumita PennathurPhD, Professor in the Department of Mechanical Engineering at UC Santa Barbara.

Details of the research presentation:

  • Michael L. StitzelPhD will present his study Deciphering Longitudinal Cell Type-Specific Defects in Diabetes Pathogenesis at the symposium, 2022 Pathway to Stop Diabetes on Friday, June 3 10:10 a.m. to 10:20 a.m. CT.
  • Sumita PennathurPhD will present his study Untethering Diabetes through Innovative Engineering at the 2022 Pathway to Stop Diabetes on Friday, June 3 10:20 a.m. to 10:30 a.m. CT.

For more information, please contact the ADA The Scientific Sessions Media Team onsite at the Ernest N. Morial Convention Center June 3-7 by phone at 504-670-4902 or by email at [email protected].

About ADA Scientific Sessions

The ADA 82n/a Scientific Sessions, the world’s largest scientific meeting focused on diabetes research, prevention and care, will be a hybrid event taking place June 3-7, 2022 at the Ernest N. Morial Convention Center in New Orleans, LA. Leading doctors, scientists and healthcare professionals from around the world will unveil cutting-edge research, treatment recommendations and advances towards a cure for diabetes. We look forward to getting back to participating in person and safely networking with colleagues while listening to the latest scientific advances and groundbreaking research presentations. Learn more and register at scientificsessions.diabetes.org and join the Science Sessions conversation on social media using #ADA2022.

About the American Diabetes Association

The American Diabetes Association (ADA) is the nation’s leading voluntary health organization fighting to bend the curve of the diabetes epidemic and help people with diabetes thrive. For 81 years, the ADA led discovery and research to treat, manage and prevent diabetes while working tirelessly for a cure. Through advocacy, program development and education, we aim to improve the quality of life for the more than 133 million Americans with diabetes or prediabetes. Diabetes brought us together, what we do next will connect us for life. To find out more or to get involved, go to diabetes.org or call 1-800-DIABETES (1-800-342-2383). Join the fight with us on Facebook (American Diabetes Association), Spanish Facebook (American Diabetes Association), LinkedIn (American Diabetes Association), Twitter (@AmDiabetesAssn), and Instagram (@AmDiabetesAssn).

Contact: daisy diaz504-670-4902
[email protected]

SOURCE American Diabetes Association